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Prednisone (Deltasone ®),. And other Tri-Cyclic AntiDepressants have a long biological half-life, therefore it takes about two weeks to accumulate in the body.prednisolone: Half-life: 1 hour: Excretion:. Eventually, this may cause the body to temporarily lose the ability to manufacture natural corticosteroids.

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. extravascular route of administration Prednisolone. for the amount of administered drug in the body to fall by one-half The half-life Meaning in.

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